किनासेस इसके अंग्रेजी अर्थ का उदाहरण

The way that HePTP effectively inhibits the MAPK signaling is by interacting with the MAP kinases Erk1, Erk2, and p38 through a short sequence in HePTP's non-catalytic N terminus termed the kinase interaction motif (KIM).

Phosphorylation of this third site by PKAs from the cAMP pathway inhibits binding of MAP kinases to HePTP and thereby upregulates the MAPK/ERK signaling cascade.

Moreover, studies involving smooth muscle cells from the atrium of the heart have shown that PKA can reduce the activation of MAP kinases in response to platelet-derived growth factor (PDGF) by phosphorylating the kinase c-Raf.

The ErbB family consists of four plasma membrane-bound receptor tyrosine kinases.

Caspase-8 activates downstream effector caspases including procaspase-3, -6, and -7, leading to activation of specific kinases.

The abrogation of ITAM activation signaling is caused by inhibition of protein tyrosine kinases of Src family, and by hydrolyzing the membrane PIP3 interrupting the further downstream signaling by the activating receptors, such as activating FcγRs, TCR, BCR and cytokine receptors (e.

Regulation of stathmin is cell cycle dependent and controlled by the cell's protein kinases in response to specific cell signals.

KIN1 and KIN2 protein kinases localize to the cytoplasmic face of the yeast plasma membrane.

Together with tyrosine kinases, PTPs regulate the phosphorylation state of many important signalling molecules, such as the MAP kinase family.

PTPs are increasingly viewed as integral components of signal transduction cascades, despite less study and understanding compared to tyrosine kinases.

The problem with K562 cells, and many other cancer cell types, is an overabundance of Aurora kinases.

These kinases play a role in the formation of spindles, separation of chromosomes, as well as cytokinesis.