फागोसाइट्स इसके अंग्रेजी अर्थ का उदाहरण

Given normal inflammatory circumstances, microbial pathogen-associated molecular patterns (PAMPs) bind with the endocytic pattern recognition receptors (PRRs) of phagocytes, which mediates neutrophil mediation or macrophage phagocytosis.

As well as endocytic PRRs, phagocytes furthermore express opsonin receptors such as Fc receptor and complement receptor 1 (CR1).

After opsonin binds to the membrane, phagocytes are attracted to the pathogen.

Fc receptors are found on a number of cells in the immune system including phagocytes like macrophages and monocytes, granulocytes like neutrophils and eosinophils, and lymphocytes of the innate immune system (natural killer cells) or adaptive immune system (e.

Activation of phagocytes is the most common function attributed to Fc receptors.

FcγRI and FcγRIIIA do not have an ITAM but can transmit an activating signal to their phagocytes by interacting with another protein that does.

When IgG molecules, specific for a certain antigen or surface component, bind to the pathogen with their Fab region (fragment antigen binding region), their Fc regions point outwards, in direct reach of phagocytes.

This also prevents agglutination (clotting) of phagocytes by antibody when there is no antigen.

The GBS capsule is probably the key virulence factor because it helps GBS escape from the host defence mechanisms interfering with phagocytic killing of GBS by human phagocytes.

As a disciple of Mechnikov, he devoted part of his research to expanding on the latter's field of interest (phagocytes, the body's means of defence against pathogens, as well as the issue of immunity and invertebrates).