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In 2013, the company purchased rights to development and commercialization of three drug candidates, recombinant blood clotting factors VIIa, VIII and IX, the latter of which is in clinical trials.

In many cases, recombinant human proteins have replaced the original animal-derived version used in medicine.

Before biosynthetic human recombinant analogues were available, porcine insulin was chemically converted into human insulin.

A solution using recombinant-gene (GMO microbial rennet) technology was developed and approved by the U.

Eventually all animal insulins made by Novo Nordisk were replaced by synthetic, recombinant 'human' insulin.

Protalix () - biopharmaceutical company focused on the development and commercialization of recombinant therapeutic proteins.

Recent studies have shown that it may be possible to produce recombinant lysosomal proteins with microorganisms such as Escherichia coli and Saccharomyces cerevisiae.

No secretory convertase is capable of cleaving the recombinant proghrelin precursor by cleavage at the single basic residue required for generation of the obestatin sequence.

1978 [[Genentech]] develop biosynthesis of recombinant human insulin in Escherichia coli bacteria using recombinant DNA technology.

Zomacton, a recombinant [growth hormone] used to treat growth failure in children.

Non-human insulins have caused allergic reactions in some patients related to the extent of purification, formation of non-neutralising antibodies is rarely observed with recombinant human insulin (insulin human rDNA) but allergy may occur in some patients.

Lysosomal proteins: Lysosomal proteins are difficult to produce recombinantly due to the number and type of post-translational modifications that they have (e.

It was engineered through recombinant DNA technology so that the penultimate lysine and proline residues on the C-terminal end of the B-chain were reversed.

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Role in V(D)J Recombination .

Recombination activating gene 1.

Recombination on the Y-chromosome does not only take place during meiosis, but virtually at every mitosis when the Y chromosome condenses, because it doesn't require pairing between chromosomes.

Recombination frequency even exceeds the frame shift mutation frequency (slipped strand mispairing) of (average fast) Y-STRs, however many recombination products may lead to infertile germ cells and "daughter out".

Recombination events (RecLOH) can be observed if YSTR databases are searched for twin alleles at 3 or more duplicated markers on the same palindrome (hairpin).

Recombination events are proportional to collisions between molecules and thus to the pressure of the gas.

(1998) A Study of Plasma Attenuation and Recombination in the Gas Target Chamber of a Divertor Simulator.

Recombination is an exothermic reaction, meaning heat releasing reaction.

Turkic peoples of Europe Recombination hotspots are regions in a genome that exhibit elevated rates of recombination relative to a neutral expectation.

Recombination hotspots result from higher DNA break formation in these regions, and apply to both mitotic and meiotic cells.

Recombination can also occur due to errors in DNA replication that lead to genomic rearrangements.

Recombination hotspots may arise from the interaction of the following selective forces: the benefit of driving genetic diversity through genomic rearrangement coupled with selection acting to maintain favorable gene combinations.