ओन्कोजीन हिंदी उपयोग और उदाहरण

जब ऐसा होता है, आद्य-ओन्कोजीन ओन्कोजीन बन जाते हैं और यह संक्रमण कोशिका में कोशिका चक्र विनियमन के सामान्य संतुलन को बिगाड़ देता है, जिससे अनियंत्रित कोशिका वृद्धि संभव हो जाती है।

""आद्य-ओन्कोजीन में उत्परिवर्तन, जो सामान्यतया ओन्कोजीन के स्थिर समकक्ष हैं, उनकी अभिव्यक्ति और क्रिया को संशोधित कर सकते हैं और उत्पाद प्रोटीन की क्रिया या मात्रा को बढ़ाते हैं।

ओन्कोजीन इसके अंग्रेजी अर्थ का उदाहरण

Thought experiments in ethics Receptor tyrosine-protein kinase erbB-2, also known as CD340 (cluster of differentiation 340), proto-oncogene Neu, Erbb2 (rodent), or ERBB2 (human), is a protein that in humans is encoded by the ERBB2 gene.

ERBB is abbreviated from erythroblastic oncogene B, a gene isolated from avian genome.

Amplification or over-expression of this oncogene has been shown to play an important role in the development and progression of certain aggressive types of breast cancer.

ErbB-2 was named for its similarity to ErbB (avian erythroblastosis oncogene B), the oncogene later found to code for EGFR.

ERBB2, a known proto-oncogene, is located at the long arm of human chromosome 17 (17q12).

HER2 is colocalised and most of the time, coamplified with the gene GRB7, which is a proto-oncogene associated with breast, testicular germ cell, gastric, and esophageal tumours.

Other examples of molecular targeted therapeutics targeting mutated oncogenes, include PLX27892 which targets mutant B-raf in melanoma.

A pioneer in the field of cancer genomics, his studies on colorectal cancers revealed that they result from the sequential accumulation of mutations in oncogenes and tumor suppressor genes.

In particular, he suggested that "cancer is caused by sequential mutations of specific oncogenes and tumor suppressor genes".

But there was no evidence that p53 played a major role in human cancers, and the gene encoding p53 (TP53) was thought to be an oncogene rather than a tumor suppressor gene.

Abnormal amounts of gene product can be correlated with disease-causing alleles, such as the overactivity of oncogenes which can cause cancer.

HRAS is a proto-oncogene in which somatic mutations in healthy people can contribute to cancer.