एपोमॉर्फिन Meaning in English
एपोमॉर्फिन शब्द का अंग्रेजी अर्थ : apomorphine
ऐसे ही कुछ और शब्द
एपोन्यूरोसिसएपोन्यूरोटिक
एपोनिम
एपोनिमस
अपोन्जाइम
एपोपेक्सी
अपोफेसिस
एपोफथेग्राम
एपोपी
एपोपोप्स
एपोपॉटिक
एपोप्स
एपोरेक्सिया
एपोरिया
अपोरिंग
एपोमॉर्फिन इसके अंग्रेजी अर्थ का उदाहरण
Contrary to its name, apomorphine does not actually contain morphine or its skeleton, nor does it bind to opioid receptors.
Historically, apomorphine has been tried for a variety of uses, including as a way to relieve anxiety and craving in alcoholics, an emetic (to induce vomiting), for treating stereotypies (repeated behaviour) in farmyard animals, and more recently in treating erectile dysfunction.
Currently, apomorphine is used in the treatment of Parkinson's disease.
The emetic properties of apomorphine are exploited in veterinary medicine to induce therapeutic emesis in canines that have recently ingested toxic or foreign substances.
A recent study indicates that apomorphine might be a suitable marker for assessing central dopamine system alterations associated with chronic heroin consumption.
There is, however, no clinical evidence that apomorphine is an effective and safe treatment regimen for opiate addiction.
While apomorphine can be used in combination with L-DOPA, the intention is usually to reduce the L-DOPA dosing, as by this stage the patient often has many of dyskinesias caused by L-DOPA and hypermobility periods.
When an episode sets in, the apomorphine is injected subcutaneously, and signs subside.
Some people use portable mini-pumps that continuously infuse them with apomorphine, allowing them to stay in the "on" state and using apomorphine as an effective monotherapy.
The main and absolute contraindication to using apomorphine is the concurrent use of adrenergic receptor antagonists; combined, they cause a severe drop in blood pressure and fainting.
Dopamine antagonists, by their nature of competing for sites at dopamine receptors, reduce the effectiveness of the agonistic apomorphine.
IV administration of apomorphine is highly discouraged, as it can crystallize in the veins and create a blood clot (thrombus) and block a pulmonary artery (pulmonary embolism).
Nausea and vomiting are common side effects when first beginning therapy with apomorphine; antiemetics such as trimethobenzamide or domperidone, dopamine antagonists, are often used while first starting apomorphine.